Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014983 | 0.91 | SIGMAR1 (0.59) | SIGMAR1HTR7P2RX7KDM4E | |
| SCHEMBL7025100 | 0.88 | ACHE (0.52) | ACHESIGMAR1HTR7P2RX7 | |
| SCHEMBL7018628 | 0.88 | ACHE (0.62) | ACHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL7017827 | 0.86 | P2RX7 (0.47) | ACHESIGMAR1HTR7P2RX7 | |
| SCHEMBL7020987 | 0.80 | MEN1 (0.59) | SIGMAR1 | |
| SCHEMBL7020012 | 0.80 | ACHE (0.52) | ACHEHTR7P2RX7 | |
| SCHEMBL7015483 | 0.80 | GRIN2B (0.48) | SIGMAR1HTR7P2RX7 | |
| SCHEMBL7021764 | 0.80 | GRIN2B (0.48) | SIGMAR1HTR7P2RX7 | |
| SCHEMBL7016337 | 0.78 | MEN1 (0.49) | SIGMAR1HTR7P2RX7 | |
| SCHEMBL7018787 | 0.78 | HTR7 (0.49) | ACHESIGMAR1HTR7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705832-B1 | Serotonergic modulators | LILLY CO ELI (GB) | 2003-08-13 | — | — | EP | disclosed |
| US-5563147-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0705832-A1 | Serotonergic modulators | LILLY INDUSTRIES LIMITED (GB) | 1996-04-10 | — | — | EP | disclosed |