Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287560 | 0.85 | ALDH1A1 (0.54) | MAPTRXRARXRBL3MBTL1ALDH1A1 | |
| SCHEMBL3999257 | 0.82 | RXRA (0.56) | MAPTRXRARXRBALDH1A1SMN1; SMN2 | |
| SCHEMBL4007795 | 0.82 | SLC22A12 (0.51) | RXRARXRBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11844159 | 0.81 | MAPK1 (0.46) | MAPTMAPK1L3MBTL1GAARAB9A | |
| SCHEMBL4003289 | 0.81 | ELANE (0.43) | MAPTMAPK1L3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL3998721 | 0.81 | HTT (0.44) | RXRARXRBHTTRXRG | |
| SCHEMBL4001117 | 0.81 | LMNA (0.52) | MAPTRXRARXRBL3MBTL1SMN1; SMN2 | |
| SCHEMBL6702501 | 0.80 | PTPN1 (0.57) | MAPTMAPK1MAOBL3MBTL1PTPN1 | |
| SCHEMBL6198744 | 0.80 | ALDH1A1 (0.60) | MAPTMAPK1MAOBPTPN1ALDH1A1 | |
| SCHEMBL1315571 | 0.79 | KDM4E (0.68) | MAPTMAPK1MAOBL3MBTL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1344780-A1 | GLUCOPYRANOSYLOXYBENZYL BENZENE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-09-17 | — | — | EP | disclosed |