Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | OGA | O60502 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873764 | 0.92 | NPC1 (0.68) | LMNANPC1RAB9APOLBEPHX2 | |
| SCHEMBL18648120 | 0.92 | NPC1 (0.68) | LMNANPC1RAB9APOLBEPHX2 | |
| SCHEMBL3026453 | 0.91 | KDM1A (0.53) | LMNANPC1RAB9APOLBEPHX2 | |
| SCHEMBL17729947 | 0.88 | EPHX2 (0.52) | LMNANPC1RAB9AEPHX2MEN1 | |
| SCHEMBL17729946 | 0.88 | EPHX2 (0.52) | LMNANPC1RAB9AEPHX2MEN1 | |
| SCHEMBL3637147 | 0.84 | L3MBTL1 (0.57) | OGAPRKAA2USP30SIGMAR1 | |
| SCHEMBL3643385 | 0.83 | L3MBTL1 (0.56) | OGAPRKAA2SIGMAR1 | |
| SCHEMBL3638459 | 0.82 | OGA (0.55) | OGAPRKAA2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4209320 | 0.82 | L3MBTL1 (0.55) | OGAPRKAA2SIGMAR1 | |
| SCHEMBL16447592 | 0.81 | ME3 (0.57) | POLBOGAPRKAA2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101941-A2 | ALPHA ACYLOXYACETAMIDES FOR KALLIKREIN AND UROKINASE INHIBITION | GENZYME CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |