Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637147 | 0.83 | L3MBTL1 (0.57) | OGAL3MBTL1PRKAA2SIGMAR1MCHR1 | |
| SCHEMBL3638457 | 0.82 | OGA (0.59) | OGAL3MBTL1PRKAA2SIGMAR1MCHR1 | |
| SCHEMBL3643385 | 0.82 | L3MBTL1 (0.56) | OGAL3MBTL1PRKAA2SIGMAR1MCHR1 | |
| SCHEMBL7105933 | 0.82 | LMNA (0.63) | OGAPRKAA2SIGMAR1 | |
| SCHEMBL4209328 | 0.81 | OGA (0.58) | OGAL3MBTL1PRKAA2SIGMAR1MCHR1 | |
| Hydrochloric Acid SCHEMBL4209320 | 0.81 | L3MBTL1 (0.55) | OGAL3MBTL1PRKAA2SIGMAR1MCHR1 | |
| SCHEMBL3641995 | 0.79 | CCR5 (0.67) | SIGMAR1 | |
| SCHEMBL7873764 | 0.78 | NPC1 (0.68) | — | |
| SCHEMBL18648120 | 0.78 | NPC1 (0.68) | — | |
| SCHEMBL13929160 | 0.77 | OGA (0.56) | OGASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173715-A2 | USE OF PIPERIDINE DERIVATIVES AS AGONISTS OF CHEMOKINE RECEPTOR ACTIVITY | Euroscreen S.A. (BE) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009010478-A2 | USE OF PIPERIDINE DERIVATIVES AS AGONISTS OF CHEMOKINE RECEPTOR ACTIVITY | EUROSCREEN S.A. (BE) | 2009-01-22 | — | — | WO | disclosed |