Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471284 | 0.86 | MEN1 (0.46) | POLBALDH1A1KMT2AMEN1HTT | |
| SCHEMBL6260852 | 0.85 | NPSR1 (0.43) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6258578 | 0.84 | ALDH1A1 (0.44) | POLBALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL6470730 | 0.83 | TP53 (0.48) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6472301 | 0.82 | MMP1 (0.47) | POLBALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6257046 | 0.82 | THRB (0.47) | POLBALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL6258893 | 0.82 | MEN1 (0.42) | POLBGAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6476368 | 0.82 | MEN1 (0.44) | POLBCHRM5CHRM1ALDH1A1GAA | |
| SCHEMBL6470989 | 0.82 | KMT2A (0.49) | POLBCHRM5CHRM1ALDH1A1MAPK1 | |
| SCHEMBL7102692 | 0.81 | MEN1 (0.41) | POLBALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370562-A1 | THIENO[2,3-D]PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002064598-A1 | THIENO'2,3-D PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | disclosed |