Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 5/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103171 | 0.87 | CA12 (0.40) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL7105765 | 0.84 | CYP4F2 (0.50) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL7106411 | 0.80 | HIF1A (0.38) | CYP4F2CYP4A11CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7103029 | 0.77 | CYP4F2 (0.62) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL8913104 | 0.75 | NLRP3 (0.49) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL7107961 | 0.74 | CYP4F2 (0.48) | CYP4F2CYP4A11SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7104876 | 0.73 | ADRB3 (0.67) | — | |
| SCHEMBL7104879 | 0.73 | ADRB3 (0.67) | — | |
| SCHEMBL7107054 | 0.72 | CYP4F2 (0.41) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL2949925 | 0.71 | ALDH1A1 (0.45) | CA12CA1CA2CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043308-B1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6353025-B1 | COMPOUNDS AS DRUGS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| EP-1043308-A1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |