Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106250 | 0.80 | CYP4F2 (0.48) | ALDH1A1L3MBTL1CA2SMN1; SMN2TDP1 | |
| SCHEMBL14496917 | 0.70 | AKR1C4 (0.49) | HIF1AALDH1A1L3MBTL1CA2SMN1; SMN2 | |
| SCHEMBL15122362 | 0.69 | KEAP1 (0.43) | ALDH1A1L3MBTL1SMN1; SMN2TDP1 | |
| Acetic Acid SCHEMBL7106412 | 0.68 | CYP4F2 (0.35) | ALDH1A1L3MBTL1CA2PRKAB2PRKAG1 | |
| SCHEMBL7103171 | 0.67 | CA12 (0.40) | ALDH1A1L3MBTL1CA2SMN1; SMN2TDP1 | |
| SCHEMBL2957178 | 0.66 | OPRK1 (0.49) | ALDH1A1L3MBTL1MAOBMAOASMN1; SMN2 | |
| SCHEMBL2927011 | 0.65 | HSD17B10 (0.48) | HIF1AALDH1A1CA2SMN1; SMN2TDP1 | |
| SCHEMBL6542262 | 0.64 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1MAOBSMN1; SMN2TDP1 | |
| SCHEMBL2926744 | 0.64 | TDP1 (0.37) | ALDH1A1CA2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL9952446 | 0.63 | TSHR (0.55) | ALDH1A1CA2SMN1; SMN2PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043308-B1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2003-09-24 | — | — | EP | disclosed |