Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13259029 | 0.85 | PPARG (0.42) | ACECAPN1MMEALDH1A1MEN1 | |
| SCHEMBL13259262 | 0.82 | ACE (0.50) | ACECAPN1CTSBCTSLCTSK | |
| SCHEMBL7653252 | 0.81 | PPID (0.51) | ACECTSBCTSLCTSK | |
| SCHEMBL24288430 | 0.80 | SIGMAR1 (0.53) | ACECAPN1CTSBMEN1KMT2A | |
| SCHEMBL5028604 | 0.80 | SIGMAR1 (0.53) | ACECAPN1CTSBMEN1KMT2A | |
| SCHEMBL19287255 | 0.79 | ATM (0.47) | ACECAPN1CTSBMAPTCTSL | |
| SCHEMBL17865652 | 0.79 | CAPN1 (0.61) | ACECAPN1CTSB | |
| SCHEMBL2369340 | 0.79 | CAPN1 (0.61) | ACECAPN1CTSB | |
| SCHEMBL16944013 | 0.79 | ACE (0.49) | ACECAPN1CTSBMEN1KMT2A | |
| SCHEMBL12468722 | 0.79 | SIGMAR1 (0.56) | ACECAPN1CTSBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749316-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-04-21 | — | — | EP | claimed |
| US-5599793-A | ANTICOAGULANTS | ELI LILLY AND COMPANY (US) | 1997-02-04 | — | — | US | claimed |
| EP-0749316-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-12-27 | — | — | EP | claimed |
| WO-1995023608-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | claimed |
| CN-100491348-C | Thrombosis resisting preparation | ASTRAZENECA AB (SE) | 2009-05-27 | — | — | CN | disclosed |
| CN-1515550-A | Thrombosis resisting preparation | — | 2004-07-28 | — | — | CN | disclosed |
| CN-1134264-C | antithrombotic agent | — | 2004-01-14 | — | — | CN | disclosed |
| EP-1361212-A1 | Peptide derivatives as antithrombotic agents | AstraZeneca AB (SE) | 2003-11-12 | — | — | EP | disclosed |
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | disclosed |
| US-5914319-A | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1999-06-22 | — | — | US | disclosed |
| EP-0749316-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-04-21 | — | — | EP | disclosed |
| US-5710130-A | HETEROCYCLIC SYNTHETIC PEPTIDES | ELI LILLY AND COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5705487-A | PEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| CN-1147205-A | antithrombotic agent | LILLY CO ELI (US) | 1997-04-09 | — | — | CN | disclosed |
| US-5599793-A | ANTICOAGULANTS | ELI LILLY AND COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| EP-0749316-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-12-27 | — | — | EP | disclosed |
| EP-0672658-A1 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1995023608-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |
| WO-1995023609-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |