Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 6/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 6/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSH | P09668 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106570 | 0.82 | ACE (0.54) | ACECTSBCAPN1CTSKCTSL | |
| SCHEMBL12468722 | 0.81 | SIGMAR1 (0.56) | ACECTSBCAPN1CTSKCTSL | |
| SCHEMBL4314482 | 0.81 | SIGMAR1 (0.56) | ACECTSBCAPN1CTSKCTSL | |
| SCHEMBL7445998 | 0.81 | CAPN1 (0.55) | ACECTSBCAPN1CTSKCTSL | |
| SCHEMBL7653252 | 0.79 | PPID (0.51) | ACECTSBCTSKCTSLCTSH | |
| SCHEMBL24760199 | 0.79 | CTSB (0.49) | ACECTSBCAPN1CTSKCTSL | |
| SCHEMBL12669995 | 0.77 | MTNR1A (0.50) | ACECTSBCAPN1 | |
| SCHEMBL16153848 | 0.76 | CTSB (0.57) | ACECTSBCAPN1CTSKCTSL | |
| SCHEMBL19287255 | 0.75 | ATM (0.47) | ACECTSBCAPN1CTSKCTSL | |
| SCHEMBL21653923 | 0.74 | CAPN1 (0.57) | ACECTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093849-A2 | PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | AMGEN INC. (US) | 2010-08-19 | — | — | WO | disclosed |