Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554934 | 0.82 | PPID (0.56) | PPIDMMP8LTA4HGPR142 | |
| SCHEMBL19287255 | 0.82 | ATM (0.47) | CTSBACECTSKCTSLCTSH | |
| SCHEMBL9185848 | 0.81 | SIGMAR1 (0.56) | PPIDMMP8LTA4H | |
| SCHEMBL7106570 | 0.81 | ACE (0.54) | CTSBACECTSKCTSL | |
| SCHEMBL7413026 | 0.80 | CTSK (0.57) | CTSBACECTSKCTSLCTSH | |
| SCHEMBL17287421 | 0.80 | PPID (0.54) | PPIDMMP8LTA4HGPR142 | |
| SCHEMBL7288757 | 0.80 | CTSK (0.57) | CTSBACECTSKCTSLCTSH | |
| SCHEMBL4847549 | 0.80 | PPID (0.54) | PPIDMMP8LTA4HGPR142 | |
| SCHEMBL9083440 | 0.80 | CTSK (0.57) | CTSBACECTSKCTSLCTSH | |
| SCHEMBL10073607 | 0.80 | PPID (0.54) | PPIDACEMMP8LTA4HGPR142 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093849-A2 | PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | AMGEN INC. (US) | 2010-08-19 | — | — | WO | disclosed |
| US-6489291-B1 | Topical composition for skin | KAO CORPORATION (JP) | 2002-12-03 | — | — | US | disclosed |