Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625038 | 0.81 | CES1 (0.32) | CES1MAPTWDR5ATM | |
| SCHEMBL7003496 | 0.73 | — | — | |
| SCHEMBL6918649 | 0.73 | ADORA3 (0.33) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6237048 | 0.70 | LMNA (0.31) | CES1MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL4622964 | 0.69 | CES1 (0.42) | CES1MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL816043 | 0.68 | ALDH1A1 (0.55) | CES1MAPTALDH1A1CYP2A6TSHR | |
| SCHEMBL7005218 | 0.66 | FABP3 (0.31) | — | |
| SCHEMBL13964953 | 0.64 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4EMAPK1LMNA | |
| SCHEMBL816534 | 0.63 | DNMT1 (0.44) | CES1MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL439492 | 0.60 | ESR1 (0.48) | CES1MAPTALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |
| EP-1219657-A1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | Japan Science and Technology Corporation (JP) | 2002-07-03 | — | — | EP | disclosed |