Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26240902 | 0.89 | ALDH1A1 (0.47) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7208472 | 0.84 | ENPP2 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL3763603 | 0.84 | IDO1 (0.58) | POLBMMP2MMP9MMP12IDO1 | |
| SCHEMBL27293680 | 0.83 | POLB (0.51) | POLBMMP2MMP9MMP12IDO1 | |
| SCHEMBL25455666 | 0.83 | POLB (0.57) | POLBMMP2MMP9MMP12IDO1 | |
| SCHEMBL19765220 | 0.83 | PRKCA (0.44) | POLBMAOBKDM4EALDH1A1 | |
| SCHEMBL6903259 | 0.82 | ALDH1A1 (0.63) | POLBMMP2MMP9MMP12IDO1 | |
| SCHEMBL7975207 | 0.81 | ALDH1A1 (0.60) | MMP2MMP9MMP12IDO1MAOB | |
| SCHEMBL24235371 | 0.81 | POLB (0.55) | POLBMMP2MMP9MMP12IDO1 | |
| SCHEMBL7656159 | 0.81 | IDO1 (0.59) | POLBMMP2MMP9MMP12IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065360-B1 | Use of 3-methylbenzyl isobutyrate as a fragrance compound | SYMRISE AG (DE) | 2013-06-19 | — | — | EP | claimed |
| US-7638479-B2 | 3-methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2009-12-29 | — | — | US | claimed |
| US-20090131299-A1 | 3-Methylbenzyl-Isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2009-05-21 | — | — | US | claimed |
| EP-1747186-B1 | Fragrant composition comprising 3-methylbenzyl-isobutyrat | SYMRISE GMBH & CO KG (DE) | 2009-03-11 | — | — | EP | claimed |
| US-7494967-B2 | 3-methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2009-02-24 | — | — | US | claimed |
| US-20070191258-A1 | 3-Methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2007-08-16 | — | — | US | claimed |
| EP-1747186-A1 | 3-METHYLBENZYL-ISOBUTYRAT | Symrise GmbH & Co. KG (DE) | 2007-01-31 | — | — | EP | claimed |
| WO-2005110967-A1 | 3-METHYLBENZYL-ISOBUTYRAT | SYMRISE GMBH & CO. KG (DE) | 2005-11-24 | — | — | WO | claimed |
| US-10202378-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-02-12 | — | — | US | disclosed |
| US-20180009805-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2018-01-11 | — | — | US | disclosed |
| EP-2065360-B1 | Use of 3-methylbenzyl isobutyrate as a fragrance compound | SYMRISE AG (DE) | 2013-06-19 | — | — | EP | disclosed |
| EP-2065360-A3 | 3-methylbenzyl isobutyrate | Symrise AG (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-7638479-B2 | 3-methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2009-12-29 | — | — | US | disclosed |
| US-7638479-B2 | 3-methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2009-12-29 | — | — | US | disclosed |
| US-7494967-B2 | 3-methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2009-02-24 | — | — | US | disclosed |
| US-7494967-B2 | 3-methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2009-02-24 | — | — | US | disclosed |
| US-20070191258-A1 | 3-Methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2007-08-16 | — | — | US | disclosed |
| US-20070191258-A1 | 3-Methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2007-08-16 | — | — | US | disclosed |
| US-20070191258-A1 | 3-Methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2007-08-16 | — | — | US | disclosed |
| US-20070191258-A1 | 3-Methylbenzyl-isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202378-B2 | Therapeutic compounds and uses thereof | TAF1, TAF1L, TAF1B | POLB 997/4885MMP2 3459/4885MMP9 3853/4885 |
| US-20090131299-A1 | 3-Methylbenzyl-Isobutyrate | ABAT, GABRB3, GABBR1 | POLB 1349/4885MMP2 3328/4885MMP9 3900/4885 |
| US-20180009805-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | TAF1, TAF1L, TAF1B | POLB 997/4885MMP2 3459/4885MMP9 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.