Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.34 |
| ▸ | PPARG | P37231 | 8/20 | 0.34 |
| ▸ | RARG | P13631 | 4/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278608 | 0.74 | CYP2C19 (0.35) | RXRAPPARGRARG | |
| SCHEMBL7645310 | 0.74 | RXRA (0.36) | RXRAPPARGRARGRARARARB | |
| SCHEMBL4440718 | 0.69 | CYP2C19 (0.33) | RXRAPPARGRARGRARARARB | |
| SCHEMBL9328498 | 0.69 | ALDH1A1 (0.34) | RXRAPPARGRARG | |
| SCHEMBL27280928 | 0.69 | RXRA (0.35) | RXRAPPARGRARGRARARARB | |
| SCHEMBL1046312 | 0.68 | NUDT1 (0.31) | NUDT1 | |
| SCHEMBL5347930 | 0.68 | RXRA (0.38) | RXRAPPARGRARGRARARARB | |
| SCHEMBL1074117 | 0.67 | RXRA (0.31) | RXRAPPARGRARGRARARARB | |
| SCHEMBL3106072 | 0.66 | CYP2D6 (0.36) | — | |
| SCHEMBL1138588 | 0.65 | RXRA (0.33) | RXRAPPARGRARGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940407-B1 | Cyclic bis-phosphites | GEN ELECTRIC (US) | 2003-12-03 | — | — | EP | disclosed |
| EP-0940407-A1 | Cyclic bis-phosphites | GENERAL ELECTRIC COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |