SCHEMBL7108192

SCHEMBL7108192

Cc1cccc2c1O[PH](=O)c1c(C)cccc1-2

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.33
DAO P14920 1/20 0.31
MYC P01106 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30594718 0.85 PDCD1 (0.40) MYCCA1CA2CA9ALDH1A1
SCHEMBL29083012 0.85 PDCD1 (0.40) MYCCA1CA2CA9ALDH1A1
SCHEMBL30165037 0.80 MYC (0.33) ACHEDAOMYC
SCHEMBL2435895 0.80 MYC (0.36) ACHEDAOMYC
SCHEMBL2430825 0.80 MYC (0.33) ACHEDAOMYC
SCHEMBL28371515 0.71 NPC1 (0.35) ACHEMYCCA1CA2CA9
SCHEMBL30594715 0.63 GABRA1 (0.34)
SCHEMBL12884761 0.63 TDP1 (0.46) ACHEDAOCA1CA2CA7
SCHEMBL16801094 0.59 KDM4E (0.44) ACHEMYC
SCHEMBL598761 0.59 TSHR (0.53) ACHEDAOMYCCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1016688-B1 Aromatic polycarbonate composition MITSUBISHI GAS CHEMICAL CO (JP) 2003-09-24 EP disclosed
US-6187896-B1 CONTAINS PHOSPHORUS COMPOUND HEAT STABILIZER MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-02-13 US disclosed
EP-1016688-A2 Aromatic polycarbonate composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-07-05 EP disclosed