Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TYMP | P19971 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248 | 0.74 | MAPK1 (0.47) | MAPK1HPGDALDH1A1TYMPLMNA | |
| SCHEMBL646139 | 0.74 | TDP1 (0.59) | MAPK1HPGDALDH1A1TYMPLMNA | |
| SCHEMBL15323916 | 0.73 | MAPK1 (0.46) | MAPK1HPGDALDH1A1TYMPLMNA | |
| SCHEMBL27621506 | 0.73 | MAPK1 (0.46) | MAPK1HPGDALDH1A1TYMPLMNA | |
| SCHEMBL6420314 | 0.73 | MAPK1 (0.46) | MAPK1HPGDALDH1A1TYMPLMNA | |
| SCHEMBL13196023 | 0.73 | MAPK1 (0.46) | MAPK1HPGDALDH1A1TYMPLMNA | |
| SCHEMBL7141531 | 0.73 | MAPK1 (0.46) | MAPK1HPGDALDH1A1TYMPLMNA | |
| SCHEMBL7043681 | 0.73 | MAPK1 (0.46) | MAPK1HPGDALDH1A1TYMPLMNA | |
| SCHEMBL5176789 | 0.73 | MAPK1 (0.46) | MAPK1HPGDALDH1A1TYMPLMNA | |
| SCHEMBL9910660 | 0.71 | MAPK1 (0.44) | MAPK1HPGDALDH1A1TYMPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9222930-B2 | Fabrication of tunneling junction for nanopore DNA sequencing | GLOBALFOUNDRIES INC. (KY) | 2015-12-29 | — | — | US | disclosed |
| US-9046511-B2 | Fabrication of tunneling junction for nanopore DNA sequencing | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140312003-A1 | FABRICATION OF TUNNELING JUNCTION FOR NANOPORE DNA SEQUENCING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-10-23 | — | — | US | disclosed |
| US-20140312002-A1 | FABRICATION OF TUNNELING JUNCTION FOR NANOPORE DNA SEQUENCING | GLOBALFOUNDRIES U.S. INC. | 2014-10-23 | — | — | US | disclosed |
| US-8858764-B2 | Electron beam sculpting of tunneling junction for nanopore DNA sequencing | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-10-14 | — | — | US | disclosed |
| US-8852407-B2 | Electron beam sculpting of tunneling junction for nanopore DNA sequencing | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-10-07 | — | — | US | disclosed |
| US-8764968-B2 | DNA sequencing using multiple metal layer structure with organic coatings forming transient bonding to DNA bases | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-07-01 | — | — | US | disclosed |
| US-20130001082-A1 | DNA SEQUENCING USING MULTIPLE METAL LAYER STRUCTURE WITH ORGANIC COATINGS FORMING TRANSIENT BONDING TO DNA BASES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-01-03 | — | — | US | disclosed |
| US-20120325656-A1 | ELECTRON BEAM SCULPTING OF TUNNELING JUNCTION FOR NANOPORE DNA SEQUENCING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120193236-A1 | ELECTRON BEAM SCULPTING OF TUNNELING JUNCTION FOR NANOPORE DNA SEQUENCING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-08-02 | — | — | US | disclosed |
| US-20120193231-A1 | DNA SEQUENCING USING MULTIPLE METAL LAYER STRUCTURE WITH ORGANIC COATINGS FORMING TRANSIENT BONDING TO DNA BASES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-08-02 | — | — | US | disclosed |
| US-8124417-B2 | Method for analyzing nucleobases on a single molecular basis | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20090155917-A1 | Method for analyzing nucleobases on a single molecular basis | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1841883-A4 | A METHOD FOR ANALYZING NUCLEOBASES ON A SINGLE MOLECULAR BASIS | JAPAN SCIENCE & TECH AGENCY (JP) | 2009-02-25 | — | — | EP | disclosed |
| EP-1841883-A1 | A METHOD FOR ANALYZING NUCLEOBASES ON A SINGLE MOLECULAR BASIS | Japan Science and Technology Agency (JP) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006070946-A1 | A METHOD FOR ANALYZING NUCLEOBASES ON A SINGLE MOLECULAR BASIS | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155917-A1 | Method for analyzing nucleobases on a single molecular basis | NT5C3B, NT5C2, SAMHD1 | MAPK1 3338/4885HPGD 4253/4885ALDH1A1 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.