Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702368 | 0.78 | OGA (0.35) | KMT2AOGAMAPTMEN1 | |
| SCHEMBL702367 | 0.78 | OGA (0.35) | KMT2AOGAMAPTMEN1 | |
| SCHEMBL717617 | 0.76 | OGA (0.38) | KMT2ANPC1RAB9ASMN1; SMN2OGA | |
| SCHEMBL652084 | 0.75 | KMT2A (0.52) | KMT2ARAB9AMEN1 | |
| SCHEMBL652083 | 0.75 | KMT2A (0.52) | KMT2ARAB9AMEN1 | |
| SCHEMBL702579 | 0.74 | OGA (0.39) | KMT2ANPC1RAB9AHSD17B10SMN1; SMN2 | |
| SCHEMBL702580 | 0.74 | OGA (0.39) | KMT2ANPC1RAB9AHSD17B10SMN1; SMN2 | |
| SCHEMBL13091418 | 0.73 | POLB (0.38) | KMT2ANPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL704131 | 0.70 | LMNA (0.34) | KMT2AOGAMAPTMEN1 | |
| SCHEMBL704130 | 0.70 | LMNA (0.34) | KMT2AOGAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |