Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 13/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702367 | 0.88 | OGA (0.35) | OGAMEN1KMT2ACCNE2CCNE1 | |
| SCHEMBL702368 | 0.88 | OGA (0.35) | OGAMEN1KMT2ACCNE2CCNE1 | |
| SCHEMBL702237 | 0.85 | MEN1 (0.35) | OGAMEN1KMT2AMAPTLMNA | |
| SCHEMBL702236 | 0.85 | MEN1 (0.35) | OGAMEN1KMT2AMAPTLMNA | |
| SCHEMBL705477 | 0.83 | MEN1 (0.33) | MEN1KMT2ALMNA | |
| SCHEMBL704131 | 0.81 | LMNA (0.34) | OGAMEN1KMT2AMAPTLMNA | |
| SCHEMBL704130 | 0.81 | LMNA (0.34) | OGAMEN1KMT2AMAPTLMNA | |
| SCHEMBL702579 | 0.80 | OGA (0.39) | OGAMEN1KMT2ANPC1MAPT | |
| SCHEMBL702580 | 0.80 | OGA (0.39) | OGAMEN1KMT2ANPC1MAPT | |
| SCHEMBL702258 | 0.77 | SETD1B (0.33) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |