Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818974 | 0.86 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL26229910 | 0.85 | KMT2A (0.49) | NPC1RAB9ASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL31532248 | 0.81 | FBP1 (0.57) | ALDH1A1GAAPOLBMAPTKMT2A | |
| SCHEMBL25245477 | 0.81 | GSK3B (0.47) | NPC1RAB9ASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL31532246 | 0.81 | GSK3B (0.47) | NPC1RAB9ASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL1699105 | 0.80 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL2658434 | 0.80 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL11377716 | 0.79 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL11393767 | 0.79 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL12095537 | 0.79 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109714-A1 | Transition metal mediated process | ABBOTT GMBH & CO. KG (DE) | 2003-06-12 | — | — | US | disclosed |
| US-20030009034-A1 | Transition metal mediated process | ABBOTT GMBH & CO. KG (DE) | 2003-01-09 | — | — | US | disclosed |
| WO-2002076960-A1 | TRANSITION METAL MEDIATED PROCESS | ABBOTT GMBH & CO. KG (DE) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030009034-A1 | Transition metal mediated process | TPMT, ABAT, TFAM | NPC1 3722/4885RAB9A 2973/4885SMN1; SMN2 2129/4885 |
| US-20030109714-A1 | Transition metal mediated process | TPMT, ABAT, TFAM | NPC1 3722/4885RAB9A 2973/4885SMN1; SMN2 2129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.