Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13525193 | 0.80 | PTGER4 (0.75) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL22591127 | 0.79 | PTGER4 (0.56) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL20996751 | 0.79 | LIPG (0.46) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL27432613 | 0.78 | FFAR1 (0.45) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL7112573 | 0.76 | HTR7 (0.57) | FFAR1FFAR4HTR7MCL1 | |
| SCHEMBL9444807 | 0.75 | PTGER3 (0.45) | FFAR4PTGER4PTGER3PTGER1PTGER2 | |
| SCHEMBL26545737 | 0.75 | FFAR1 (0.47) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL11673570 | 0.74 | FFAR1 (0.49) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL9890647 | 0.74 | PTGER1 (0.57) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL19612745 | 0.74 | NAAA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047665-B1 | MATRIX METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-10-22 | — | — | EP | disclosed |
| US-6350907-B1 | PEPTIDE ENZYME INHIBITORS | PFIZER INC | 2002-02-26 | — | — | US | disclosed |
| EP-1047665-A1 | MATRIX METALLOPROTEASE INHIBITORS | Pfizer Limited (GB) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999035124-A1 | MATRIX METALLOPROTEASE INHIBITORS | PFIZER LIMITED (GB) | 1999-07-15 | — | — | WO | disclosed |