Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345015 | 0.85 | CACNA1B (0.61) | CPB2SMN1; SMN2NPC1RAB9ACACNA1B | |
| SCHEMBL5356979 | 0.77 | CACNA1B (0.59) | CPB2SMN1; SMN2NPC1RAB9ACACNA1B | |
| SCHEMBL528123 | 0.77 | CA12 (0.67) | SMN1; SMN2NPC1RAB9ALMNACTSL | |
| SCHEMBL16696334 | 0.74 | FAAH (0.56) | NPC1RAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL5347346 | 0.72 | CACNA1B (0.77) | CPB2SMN1; SMN2NPC1RAB9ACACNA1B | |
| SCHEMBL5351703 | 0.72 | CACNA1B (0.78) | CPB2SMN1; SMN2NPC1RAB9ACACNA1B | |
| SCHEMBL5354917 | 0.72 | CACNA1B (0.71) | CPB2SMN1; SMN2NPC1RAB9ACACNA1B | |
| SCHEMBL5350332 | 0.72 | CACNA1B (0.71) | CPB2SMN1; SMN2NPC1RAB9ACACNA1B | |
| SCHEMBL5354609 | 0.72 | ALDH1A1 (0.51) | CPB2SMN1; SMN2NPC1RAB9ACACNA1B | |
| SCHEMBL7110440 | 0.71 | YAP1 (0.41) | SMN1; SMN2NPC1RAB9ACACNA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | CPB2 3716/4885SMN1; SMN2 297/4885NPC1 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.