SCHEMBL7110463

SCHEMBL7110463

C=C(C)C(=O)NCC(C)OC(=O)COC(=O)C(C(=O)OCC(=O)OC(C)CNC(=O)C(=C)C)C(CC(=O)O)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7110459 0.83 TDP1 (0.32) TDP1
SCHEMBL7632559 0.77 TDP1 (0.31) TDP1
SCHEMBL5157071 0.74 KDM6B (0.33)
SCHEMBL7110877 0.74
SCHEMBL7110870 0.72 TSHR (0.32)
SCHEMBL11419538 0.70 FAAH (0.36)
SCHEMBL16805864 0.70 TSHR (0.38)
SCHEMBL339839 0.69 TSHR (0.35)
SCHEMBL7115526 0.67 TSHR (0.32)
SCHEMBL24513273 0.66 TGFBR1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030078339-A1 Degradable cross-linking agents and cross-linked network polymers formed therewith ACCESS PHARMACEUTICALS, INC. 2003-04-24 US disclosed
US-6521431-B1 Cosmetic and drug-time release agents; hazardous waste remediation, metal chelation, wound healing agents ACCESS PHARMACEUTICALS, INC. 2003-02-18 US disclosed
EP-1263849-A1 DEGRADABLE CROSS-LINKING AGENTS AND CROSS-LINKED NETWORK POLYMERS FORMED THEREWITH Access Pharmaceuticals, Inc. (US) 2002-12-11 EP disclosed
WO-2000078846-A1 DEGRADABLE CROSS-LINKING AGENTS AND CROSS-LINKED NETWORK POLYMERS FORMED THEREWITH ACCESS PHARMACEUTICALS, INC. (US) 2000-12-28 WO disclosed