SCHEMBL339839

SCHEMBL339839

C=C(C)C(=O)NCC(C)OC(=O)C(C)O

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TGFBR1 P36897 1/20 0.33
MTNR1A P48039 2/20 0.32
MTNR1B P49286 2/20 0.32
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
RXFP1 Q9HBX9 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10016884 0.94 TSHR (0.32) TSHRMEN1KMT2A
SCHEMBL7110870 0.84 TSHR (0.32) TSHR
SCHEMBL16805864 0.84 TSHR (0.38) TSHRTGFBR1MTNR1AMTNR1BKDM4E
SCHEMBL339899 0.82 TSHR (0.33) TSHRMEN1KMT2ATGFBR1THRB
SCHEMBL7115526 0.81 TSHR (0.32) TSHRKDM4E
SCHEMBL339382 0.80 TSHR (0.31) TSHR
SCHEMBL24513273 0.80 TGFBR1 (0.37) TSHRMEN1KMT2ATGFBR1MTNR1A
SCHEMBL7110877 0.79
SCHEMBL8447931 0.79 MTNR1A (0.33) TSHRTGFBR1MTNR1AMTNR1BMAPT
SCHEMBL9399525 0.79 TSHR (0.34) TSHRTGFBR1MTNR1AMTNR1BTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12138274-B2 Compositions and methods for the treatment of peripheral artery disease and cardiopulmonary diseases BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2024-11-12 US disclosed
US-20130251778-A1 MEDICAL DEVICES FOR THERAPEUTIC AGENT DELIVERY WITH POLYMERIC REGIONS THAT CONTAIN COPOLYMERS HAVING BOTH SOFT SEGMENTS AND UNIFORM LENGTH HARD SEGMENTS BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-09-26 US disclosed
EP-1979014-B1 MEDICAL DEVICES FOR THERAPEUTIC AGENT DELIVERY WITH POLYMERIC REGIONS THAT CONTAIN COPOLYMERS HAVING BOTH SOFT SEGMENTS AND UNIFORM LENGTH HARD SEGMENTS BOSTON SCIENT LTD (BB) 2013-07-03 EP disclosed
US-8440214-B2 Medical devices for therapeutic agent delivery with polymeric regions that contain copolymers having both soft segments and uniform length hard segments BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-05-14 US disclosed
US-20120015034-A1 TEMPERATURE SENSITIVE POLYMERS UNIVERSITEIT UTRECHT (NL) 2012-01-19 US disclosed
EP-1979014-A2 MEDICAL DEVICES FOR THERAPEUTIC AGENT DELIVERY WITHOUT POLYMERIC REGIONS THAT CONTAIN COPOLYMERS HAVINT BOTH SOFT SEGMENTS AND UNIFORM LENGHT HARD SEGMENTS Boston Scientific Scimed, Inc. (US) 2008-10-15 EP disclosed
US-7425581-B2 Temperature sensitive polymers UNIVERSITEIT UTRECHT 2008-09-16 US disclosed
WO-2007089435-A2 MEDICAL DEVICES FOR THERAPEUTIC AGENT DELIVERY BOSTON SCIENTIFIC SCIMED, INC. (US) 2007-08-09 WO disclosed
US-20070178136-A1 Medical devices for therapeutic agent delivery with polymeric regions that contain copolymers having both soft segments and uniform length hard segments BOSTON SCIENTIFIC SCIMED, INC. 2007-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015034-A1 TEMPERATURE SENSITIVE POLYMERS LCT, LDHA, LDHB TSHR 4451/4885MEN1 3434/4885KMT2A 2446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.