SCHEMBL7110870

SCHEMBL7110870

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nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7110877 0.94
SCHEMBL7115526 0.88 TSHR (0.32) TSHR
SCHEMBL339839 0.84 TSHR (0.35) TSHR
SCHEMBL5157071 0.83 KDM6B (0.33) TSHR
SCHEMBL10016884 0.79 TSHR (0.32) TSHR
SCHEMBL16805864 0.79 TSHR (0.38) TSHR
SCHEMBL11419538 0.76 FAAH (0.36) TSHR
SCHEMBL24513273 0.75 TGFBR1 (0.37) TSHR
SCHEMBL8447931 0.74 MTNR1A (0.33) TSHR
SCHEMBL9399525 0.74 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030078339-A1 Degradable cross-linking agents and cross-linked network polymers formed therewith ACCESS PHARMACEUTICALS, INC. 2003-04-24 US disclosed
US-6521431-B1 Cosmetic and drug-time release agents; hazardous waste remediation, metal chelation, wound healing agents ACCESS PHARMACEUTICALS, INC. 2003-02-18 US disclosed