SCHEMBL711052

SCHEMBL711052

CC(CCO)=C(C)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.37
FNTB P49356 2/20 0.37
THRB P10828 1/20 0.37
PGGT1B P53609 1/20 0.37
LMNA P02545 1/20 0.33
SLC15A2 Q16348 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CAMK2A Q9UQM7 1/20 0.33
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
GPR84 Q9NQS5 1/20 0.31
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
OR51E2 Q9H255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8438238 1.00 FNTA (0.37) FNTAFNTBTHRBPGGT1BLMNA
SCHEMBL4988237 1.00 FNTA (0.37) FNTAFNTBTHRBPGGT1BLMNA
Methacrylic Acid SCHEMBL29808091 0.91 THRB (0.32) FNTAFNTBTHRBPGGT1B
SCHEMBL715889 0.80 GPR84 (0.52) FNTAFNTBTHRBPGGT1BLMNA
SCHEMBL3841640 0.78 HDAC3 (0.48) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL811388 0.78 LMNA (0.52) FNTAFNTBTHRBPGGT1BLMNA
SCHEMBL21044318 0.78 LMNA (0.33) LMNASLC15A2ALDH1A1CAMK2AFFAR3
SCHEMBL21044316 0.78 LMNA (0.33) LMNASLC15A2ALDH1A1CAMK2AFFAR3
SCHEMBL3841638 0.78 HDAC3 (0.48) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL28382991 0.78 FNTA (0.37) FNTAFNTBTHRBPGGT1BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180318473-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2018-11-08 US claimed
EP-3345631-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES Abraxis BioScience, LLC (US) 2018-07-11 EP claimed
EP-3345632-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES Abraxis BioScience, LLC (US) 2018-07-11 EP claimed
US-9982184-B2 Terpolymer compositions EVONIK CORPORATION (US) 2018-05-29 US claimed
US-9954126-B2 Three-dimensional photovoltaic devices including cavity-containing cores and methods of manufacture Q1 NANOSYSTEMS CORPORATION (US) 2018-04-24 US claimed
EP-3286279-A1 FRICTION REDUCING TERPOLYMER COMPOSITIONS AND METHOD OF FRACTURING Evonik Corporation (US) 2018-02-28 EP claimed
EP-1861070-B1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2018-01-17 EP claimed
US-20170203012-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2017-07-20 US claimed
WO-2016172067-A1 FRICTION REDUCING TERPOLYMER COMPOSITIONS AND METHOD OF FRACTURING EVONIK CORPORATION (US) 2016-10-27 WO claimed
US-20160304769-A1 TERPOLYMER COMPOSITIONS EVONIK CORPORATION 2016-10-20 US claimed
US-20050137684-A1 Stent with therapeutically active drug coated thereon PFIZER INC 2005-06-23 US claimed
US-20050085902-A1 Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures,Including delivery using a modified stent CARDINAL HEALTH SWITZERLAND 515 GmbH (CH) 2005-04-21 US claimed
EP-1407726-A1 Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Cordis Corporation (US) 2004-04-14 EP claimed
US-6585764-B2 Stent with therapeutically active dosage of rapamycin coated thereon CORDIS CORPORATION 2003-07-01 US claimed
EP-0587565-B1 INTRAOCULAR LENS WITH HAPTIC ANCHOR PLATE MEDEVEC LICENSING BV (NL) 1998-08-19 EP claimed
EP-0587565-A4 INTRAOCULAR LENS WITH HAPTIC ANCHOR PLATE. CUMMING STUART J (US) 1995-02-22 EP claimed
EP-0587565-A1 INTRAOCULAR LENS WITH HAPTIC ANCHOR PLATE MEDEVEC LICENSING B.V. (NL) 1994-03-23 EP claimed
WO-1992021304-A1 INTRAOCULAR LENS WITH HAPTIC ANCHOR PLATE CUMMING STUART J (US) 1992-12-10 WO claimed
US-5047051-A Intraocular lens with haptic anchor plate THE NICE TRUST, A TRUST OF THE ISLE OF MAN 1991-09-10 US claimed
EP-0274721-A2 Polymers containing amino groups, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170203012-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES MIF, MKI67, ABCB11 FNTA 1546/4885FNTB 3933/4885THRB 4027/4885
US-20180318473-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES MIF, MKI67, ABCB11 FNTA 1546/4885FNTB 3933/4885THRB 4027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.