SCHEMBL7110683

SCHEMBL7110683

C=C(C(=O)O)N1C(=O)C=CC1=O

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.34
NSD2 O96028 1/20 0.34
G6PD P11413 1/20 0.34
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
PTGS1 P23219 5/20 0.32
PTGS2 P35354 5/20 0.32
MGLL Q99685 2/20 0.32
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15301140 0.78 TDP1 (0.32) MGLLGSK3AGSK3B
SCHEMBL12038009 0.78 ALDH1A1 (0.36) MGLLGSK3AGSK3B
SCHEMBL4463617 0.73 ALDH1A1 (0.39) MGLLGSK3AGSK3B
SCHEMBL13531991 0.73 GSK3A (0.32) MGLLGSK3AGSK3B
SCHEMBL9443365 0.72
SCHEMBL711961 0.69 NSD2 (0.41) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL28434369 0.69 GSK3A (0.49) MGLLGSK3AGSK3B
SCHEMBL10516220 0.69 MGLL (0.35) MGLLGSK3AGSK3B
SCHEMBL4857568 0.69 MGLL (0.41) MGLLGSK3AGSK3B
SCHEMBL11050099 0.69 CA12 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3849780-B1 THREE-DIMENSIONAL OBJECT AND MANUFACTURING METHOD THEREOF ADMATEC EUROPE B V (NL) 2024-06-12 EP claimed
CN-109608379-A A kind of-two polyethylene glycol of protein cross agent maleimide-acrylic acid succinimide ester preparation method 苏州昊帆生物股份有限公司 2019-04-12 CN claimed
EP-1359461-A2 Low loss electro-optic polymers and devices made therefrom Corning Incorporated (US) 2003-11-05 EP claimed
US-20030201429-A1 Low loss electro-optic polymers and devices made therefrom CORNING INCORPORATED 2003-10-30 US claimed
CN-114806476-A Epoxy resin conductive adhesive containing composite conductive filler and preparation method thereof 罗卫中 2022-07-29 CN disclosed
EP-3221698-B1 POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF Global Life Sciences Solutions Operations UK Ltd (GB) 2021-02-17 EP disclosed
CN-109608379-A A kind of-two polyethylene glycol of protein cross agent maleimide-acrylic acid succinimide ester preparation method 苏州昊帆生物股份有限公司 2019-04-12 CN disclosed
EP-1359461-A2 Low loss electro-optic polymers and devices made therefrom Corning Incorporated (US) 2003-11-05 EP disclosed
US-20030201429-A1 Low loss electro-optic polymers and devices made therefrom CORNING INCORPORATED 2003-10-30 US disclosed
CN-1295680-A Photopolymerization compositions including maleimides and processes for using the same FIRST CHEMICAL CORP (US) 2001-05-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030201429-A1 Low loss electro-optic polymers and devices made therefrom PPOX, GALE, ELOVL3 DDAH1 3786/4885NSD2 4832/4885G6PD 2499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.