Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | EIF4E | P06730 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7114730 | 0.99 | PNP (0.55) | PNPSMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL1713573 | 0.92 | PNP (0.64) | PNPSMN1; SMN2ALDH1A1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL7773119 | 0.91 | PNP (0.63) | PNPSMN1; SMN2ALDH1A1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL5718893 | 0.91 | PNP (0.63) | PNPSMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL21883489 | 0.86 | SMN1; SMN2 (0.56) | PNPSMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL16028279 | 0.86 | TYMS (0.53) | PNPSMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL9667710 | 0.86 | ALDH1A1 (0.52) | PNPSMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL7111737 | 0.84 | PNP (0.49) | PNPSMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL9667719 | 0.84 | SMN1; SMN2 (0.49) | PNPSMN1; SMN2ALDH1A1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL6258586 | 0.83 | PNP (0.48) | PNPSMN1; SMN2ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186978-A1 | Novel telomerase inhibitors | PHARMACIA ITALIA, SPA (IT) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186978-A1 | Novel telomerase inhibitors | TERT, TERF2IP, TERF2 | PNP 646/4885SMN1; SMN2 2003/4885ALDH1A1 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.