Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111074 | 0.90 | PNP (0.44) | MEN1KMT2AADORA2APNP | |
| SCHEMBL7120152 | 0.89 | PNP (0.45) | MEN1KMT2AADORA2APNP | |
| SCHEMBL7111860 | 0.86 | PNP (0.45) | MEN1KMT2ALMNAADORA2APNP | |
| SCHEMBL7117280 | 0.86 | PNP (0.45) | MEN1KMT2ALMNAADORA2APNP | |
| SCHEMBL7110374 | 0.85 | SMN1; SMN2 (0.48) | KMT2ALMNAADORA2ATYMSPNP | |
| SCHEMBL6548067 | 0.85 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ALMNAPDE5A | |
| SCHEMBL7118541 | 0.83 | PNP (0.40) | MEN1KMT2AADORA2APNPCASR | |
| SCHEMBL7113849 | 0.83 | PNP (0.43) | MEN1KMT2AADORA2APNP | |
| SCHEMBL7113168 | 0.83 | PNP (0.43) | MEN1KMT2AADORA2APNP | |
| SCHEMBL7113866 | 0.83 | PNP (0.39) | ADORA2APNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186978-A1 | Novel telomerase inhibitors | PHARMACIA ITALIA, SPA (IT) | 2003-10-02 | — | — | US | claimed |
| WO-2001096339-A1 | NOVEL TELOMERASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-20 | — | — | WO | claimed |
| US-20030186978-A1 | Novel telomerase inhibitors | PHARMACIA ITALIA, SPA (IT) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186978-A1 | Novel telomerase inhibitors | TERT, TERF2IP, TERF2 | L3MBTL1 963/4885MEN1 1870/4885KMT2A 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.