Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 6/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 3/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112348 | 0.89 | CPA1 (0.47) | CTRB1TRPM8CTSBCTSLCPA1 | |
| SCHEMBL7663931 | 0.84 | CPA1 (0.55) | CPA1 | |
| SCHEMBL7810113 | 0.83 | KLK5 (0.60) | CTSBCTSL | |
| SCHEMBL2630734 | 0.83 | KLK5 (0.60) | CTSBCTSL | |
| SCHEMBL6861203 | 0.83 | KLK5 (0.60) | CTSBCTSL | |
| SCHEMBL3471057 | 0.83 | KLK5 (0.60) | CTSBCTSL | |
| SCHEMBL7111203 | 0.83 | KLK5 (0.60) | CTSBCTSL | |
| SCHEMBL7815696 | 0.83 | KLK5 (0.60) | CTSBCTSL | |
| SCHEMBL8838391 | 0.83 | KLK5 (0.60) | CTSBCTSL | |
| SCHEMBL6812568 | 0.83 | TRPM8 (0.60) | CTRB1TRPM8CTSBCTSLSPPL2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030040644-A1 | Synthesis of nitroalcohol diastereomers | PHARM-ECO LABORATORIES, INC. | 2003-02-27 | — | — | US | disclosed |
| US-6462221-B1 | 3-SUBSTITUTED-3-AMINO-2-HYDROXYPROPANOIC ACID SALT OR 1-NITRO-3-SUBSTITUTE-3-AMINO-2-HYDROXYPROPANOL DIASTEREOMERS OBTAINED FROM SIMULATED MOVING BED SEPARATION | PHARM-ECO LABORATORIES, INC. | 2002-10-08 | — | — | US | disclosed |
| EP-1159253-A2 | SYNTHESIS OF NITROALCOHOL DIASTEREOMERS | Johnson Matthey Pharmaceutical Materials Inc (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000050378-A9 | SYNTHESIS OF NITROALCOHOL DIASTEREOMERS | — | 2001-08-23 | — | — | WO | disclosed |
| EP-0769003-B1 | AMINO ACID-DERIVED DIAMINOPROPANOLS | PHARMECO LAB INC (US) | 2001-05-16 | — | — | EP | disclosed |
| EP-1059285-A2 | Process for the preparation of 1,3-diamino-2-propanol and 1,3-diamino-2-propanone derivatives | Pharm-Eco Laboratories, Inc. (US) | 2000-12-13 | — | — | EP | disclosed |
| WO-2000050378-A2 | SYNTHESIS OF NITROALCOHOL DIASTEREOMERS | PHARM-ECO LABORATORIES, INC. (US) | 2000-08-31 | — | — | WO | disclosed |
| US-6063963-A | Amino acid-derived diaminopropanols | PHARM-ECO LABORATORIES, INC. (US) | 2000-05-16 | — | — | US | disclosed |
| US-5631405-A | Method of forming amino acid-derived diaminopropanols useful as chemical intermediates for protease-inhibitors | PHARM-ECO LABORATORIES, INCORPORATED (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0769003-A1 | AMINO ACID-DERIVED DIAMINOPROPANOLS | Pharmeco Laboratories, Inc. (US) | 1997-04-23 | — | — | EP | disclosed |
| US-5618966-A | Method forming protease inhibitor synthetic intermediates | PHARM-ECO LABORATORIES, INCORPORATED (US) | 1997-04-08 | — | — | US | disclosed |
| US-5599994-A | Amino acid-derived diaminopropanols | PHARM-ECO LABORATORIES, INC. (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996001788-A2 | AMINO ACID-DERIVED DIAMINOPROPANOLS | PHARM-ECO LABORATORIES, INCORPORATED (US) | 1996-01-25 | — | — | WO | disclosed |
| US-5475138-A | Method preparing amino acid-derived diaminopropanols | PHARM-ECO LABORATORIES INCORPORATED (US) | 1995-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040644-A1 | Synthesis of nitroalcohol diastereomers | ALDH7A1, ADRA1A, ADH1A | CTRB1 2741/4885TRPM8 4819/4885CTSB 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.