SCHEMBL7092147

SCHEMBL7092147

CCCCn1cnc2nc3cc(Cl)ccc3nc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
NPC1 O15118 1/20 0.41
CTSL P07711 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.40
HRH4 Q9H3N8 2/20 0.39
ADORA2A P29274 1/20 0.38
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HSD17B10 Q99714 1/20 0.37
HCRTR1 O43613 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
CCNE1 P24864 3/20 0.37
CDK2 P24941 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10524592 0.96 TLR8 (0.40) TSHRNPC1CTSLMEN1KMT2A
SCHEMBL7034506 0.86 DPP4 (0.42) NPC1MEN1KMT2AHRH4KDM4E
SCHEMBL7111137 0.79 ALDH1A1 (0.48) TSHRMEN1KMT2AKDM4EGAA
SCHEMBL7033155 0.77 HIF1A (0.44) NPC1MEN1KMT2ALMNAKDM4E
SCHEMBL11557672 0.75 LMNA (0.60) TSHRNPC1LMNAKDM4EGAA
SCHEMBL7877110 0.71 LMNA (0.55) NPC1LMNAKDM4EGAAMAPT
SCHEMBL11722891 0.70 MAPT (0.43) MEN1KMT2AHRH4KDM4EMAPT
SCHEMBL7036789 0.69 FGFR1 (0.56) KDM4EMAPTALDH1A1HPGDHCRTR1
SCHEMBL7034909 0.67 KDM4E (0.42) TSHRNPC1MEN1KMT2ALMNA
SCHEMBL11722380 0.66 NPC1 (0.45) NPC1KDM4EALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37962-E1 Photopolymerizable composition containing a sensitizing dye and a titanocene compound FUJI PHOTO FILM CO., LTD. (JP) 2003-01-07 US disclosed
US-5424442-A Eliminates the need to use organic solvents and other solubilizing additives FUJI PHOTO FILM CO., LTD. (JP) 1995-06-13 US disclosed
US-5385807-A Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1995-01-31 US disclosed
US-5250692-A Water-soluble methine compounds useful in photographic silver halide emulsions FUJI PHOTO FILM CO., LTD. (JP) 1993-10-05 US disclosed
EP-0520364-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1992-12-30 EP disclosed