Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805376 | 0.83 | TLR8 (0.41) | MEN1CYP1A2KMT2ACYP2C9CRHBP | |
| SCHEMBL7111137 | 0.75 | ALDH1A1 (0.48) | MEN1CYP1A2KMT2ACYP2C9CRHBP | |
| SCHEMBL327116 | 0.71 | MTNR1A (0.56) | KMT2AALDH1A1POLBTLR8CNR2 | |
| SCHEMBL4554026 | 0.69 | CDK4 (0.81) | TLR8LMNAMAPK1 | |
| SCHEMBL30495581 | 0.69 | CDK4 (0.81) | TLR8LMNAMAPK1 | |
| SCHEMBL7541745 | 0.69 | TLR7 (0.47) | KDM4ETLR8SLC9A1LMNAGLO1 | |
| SCHEMBL30376 | 0.68 | CDK4 (0.82) | TLR8LMNAMAPK1 | |
| SCHEMBL31454116 | 0.68 | CDK4 (0.82) | TLR8LMNAMAPK1 | |
| SCHEMBL4976386 | 0.68 | CDK4 (0.82) | TLR8LMNAMAPK1 | |
| SCHEMBL19748097 | 0.68 | CDK4 (0.82) | TLR8LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101537-B2 | Tricyclic quinoxaline and quinoline derivatives as a UV filter | MERCK PATENTGESELLSCHAFT (DE) | 2006-09-05 | — | — | US | disclosed |
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | MERCK PATENT GMBH (DE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | CUTA, CYP1B1, TPH1 | MEN1 683/4885CYP1A2 29/4885KMT2A 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.