SCHEMBL7112202

SCHEMBL7112202

O=S(=O)(Nc1ccccc1OCC1CCN(c2ccncc2)CC1)c1ccc2cc(Br)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
F10 P00742 9/20 0.48
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
IKBKB O14920 1/20 0.40
CHUK O15111 1/20 0.40
TPSAB1 Q15661 1/20 0.40
LSS P48449 1/20 0.40
OGT O15294 1/20 0.40
POLB P06746 1/20 0.40
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
GLO1 Q04760 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
F2 P00734 1/20 0.39
RAD52 P43351 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5633263 0.93 F10 (0.55) F10MEN1KMT2AIKBKBCHUK
SCHEMBL6578432 0.86 F10 (0.46) F10MEN1KMT2ALSSALDH1A1
SCHEMBL5631650 0.80 ALDH1A1 (0.56) F10MEN1KMT2ATPSAB1ALDH1A1
SCHEMBL7118163 0.78 F10 (0.44) F10LSS
SCHEMBL7124112 0.77 F2 (0.46) F10MEN1KMT2ALSSALDH1A1
SCHEMBL7120480 0.75 KMT2A (0.47) F10MEN1KMT2ALSSALDH1A1
SCHEMBL7112884 0.75 SLC6A4 (0.46) MEN1KMT2A
SCHEMBL6576136 0.75 CYP3A4 (0.47) F10MEN1KMT2ALSSALDH1A1
SCHEMBL8112377 0.72 TPSAB1 (0.61) F10TPSAB1LSS
SCHEMBL5632390 0.72 ALDH1A1 (0.45) F10MEN1KMT2AIKBKBCHUK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030207882-A1 Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents ZENECA LIMITED 2003-11-06 US claimed
US-20030207882-A1 Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents ZENECA LIMITED 2003-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207882-A1 Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents F2, SERPINC1, F11 F10 8/4885MEN1 594/4885KMT2A 2234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.