SCHEMBL7112285

SCHEMBL7112285

O=C1c2ccccc2C(=O)c2c(NCCOCCO)cccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.62
MEN1 O00255 5/20 0.62
MAPT P10636 4/20 0.62
POLB P06746 3/20 0.62
ALDH1A1 P00352 3/20 0.62
EGFR P00533 2/20 0.62
MAPK1 P28482 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
BLM P54132 2/20 0.62
HTT P42858 2/20 0.62
RAD52 P43351 2/20 0.62
LMNA P02545 1/20 0.62
RECQL P46063 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
NSD2 O96028 2/20 0.57
FGB P02675 1/20 0.57
MMP14 P50281 1/20 0.57
TOP2B Q02880 1/20 0.52
RAB9A P51151 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31616803 0.99 KMT2A (0.61) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL15859645 0.96 NSD2 (0.61) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL8426997 0.90 TOP2B (0.64) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL27294872 0.89 TOP2B (0.62) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL20334294 0.87 NSD2 (0.52) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL4732627 0.85 MEN1 (0.72) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL20334359 0.84 TOP2B (0.57) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL8429091 0.84 TOP2B (0.57) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL6678121 0.82 MAPT (0.77) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL32679354 0.82 MAPT (0.77) KMT2AMEN1MAPTPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5948268-A DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER NIPPON SHOKUBAI CO., LTD. (JP) 1999-09-07 US claimed
US-11378546-B2 PH Meter PARKER HANNIFIN CORP (US) 2022-07-05 US disclosed
EP-3734264-A1 PH METER Parker Hannifin Corporation (US) 2020-11-04 EP disclosed
US-20200064307-A1 pH METER PARKER HANNIFIN CORP (US) 2020-02-27 US disclosed
US-20150346144-A1 PH METER PARKER-HANNIFIN CORPORATION 2015-12-03 US disclosed
US-20150346144-A1 PH METER PARKER-HANNIFIN CORPORATION 2015-12-03 US disclosed
WO-2014106066-A1 PH METER SENOVA SYSTEMS, INC. (US) 2014-07-03 WO disclosed
US-20030203975-A1 Anti-cancer agents BTG INTERNATIONAL LIMITED (GB) 2003-10-30 US disclosed
EP-0761604-B1 An agent for water treatment NIPPON CATALYTIC CHEM IND (JP) 2000-06-14 EP disclosed
US-5948268-A DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER NIPPON SHOKUBAI CO., LTD. (JP) 1999-09-07 US disclosed
EP-0761604-A2 An agent for water treatment NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030203975-A1 Anti-cancer agents TOP2B, TOP2A, TOP1 KMT2A 3724/4885MEN1 3787/4885MAPT 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.