SCHEMBL15859645

SCHEMBL15859645

O=C1c2cccc(NCCOCCO)c2C(=O)c2cccc(NCCOCCO)c21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.61
FGB P02675 1/20 0.61
MMP14 P50281 1/20 0.61
KMT2A Q03164 4/20 0.56
MAPT P10636 4/20 0.56
MEN1 O00255 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
POLB P06746 2/20 0.56
BLM P54132 2/20 0.56
EGFR P00533 2/20 0.56
MAPK1 P28482 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
ALDH1A1 P00352 2/20 0.56
HTT P42858 2/20 0.56
LMNA P02545 1/20 0.56
RAD52 P43351 1/20 0.56
RECQL P46063 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
TOP2B Q02880 1/20 0.49
TERT O14746 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7112285 0.96 KMT2A (0.62) NSD2FGBMMP14KMT2AMAPT
SCHEMBL31616803 0.94 KMT2A (0.61) NSD2FGBMMP14KMT2AMAPT
SCHEMBL20334294 0.91 NSD2 (0.52) NSD2FGBMMP14KMT2AMAPT
SCHEMBL8426997 0.88 TOP2B (0.64) NSD2FGBMMP14KMT2AMAPT
SCHEMBL27294872 0.87 TOP2B (0.62) NSD2FGBMMP14KMT2AMAPT
SCHEMBL9357997 0.84 NSD2 (0.77) NSD2FGBMMP14KMT2AMAPT
SCHEMBL8429091 0.82 TOP2B (0.57) NSD2FGBMMP14KMT2AMAPT
SCHEMBL20334359 0.82 TOP2B (0.57) NSD2FGBMMP14KMT2AMAPT
SCHEMBL13434538 0.81 TERT (0.53) NSD2FGBMMP14KMT2AMAPT
SCHEMBL375063 0.81 NSD2 (0.77) NSD2FGBMMP14KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11378546-B2 PH Meter PARKER HANNIFIN CORP (US) 2022-07-05 US disclosed
EP-3734264-A1 PH METER Parker Hannifin Corporation (US) 2020-11-04 EP disclosed
US-20200064307-A1 pH METER PARKER HANNIFIN CORP (US) 2020-02-27 US disclosed
US-20150346144-A1 PH METER PARKER-HANNIFIN CORPORATION 2015-12-03 US disclosed
US-20150346144-A1 PH METER PARKER-HANNIFIN CORPORATION 2015-12-03 US disclosed
WO-2014106066-A1 PH METER SENOVA SYSTEMS, INC. (US) 2014-07-03 WO disclosed