SCHEMBL20334294

SCHEMBL20334294

Nc1ccc(N)c2c1C(=O)c1cccc(NCCOCCO)c1C2=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NSD2 O96028 2/20 0.52
▸ MMP14 P50281 2/20 0.52
▸ FGB P02675 2/20 0.52
▸ KMT2A Q03164 8/20 0.48
▸ MEN1 O00255 7/20 0.48
▸ POLB P06746 5/20 0.48
▸ MAPT P10636 5/20 0.48
▸ SMN1; SMN2 Q16637 4/20 0.48
▸ BLM P54132 3/20 0.48
▸ ALDH1A1 P00352 3/20 0.48
▸ MAPK1 P28482 3/20 0.48
▸ L3MBTL1 Q9Y468 3/20 0.48
▸ NPSR1 Q6W5P4 2/20 0.48
▸ EGFR P00533 2/20 0.48
▸ HTT P42858 2/20 0.48
▸ LMNA P02545 1/20 0.48
▸ RAD52 P43351 1/20 0.48
▸ RECQL P46063 1/20 0.48
▸ TERT O14746 2/20 0.44
▸ TOP2B Q02880 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15859645 0.91 NSD2 (0.61) NSD2MMP14FGBKMT2AMEN1
SCHEMBL7112285 0.87 KMT2A (0.62) NSD2MMP14FGBKMT2AMEN1
SCHEMBL10581062 0.87 NSD2 (0.63) NSD2MMP14FGBKMT2AMEN1
SCHEMBL20334197 0.86 NSD2 (0.43) NSD2MMP14FGBKMT2AMEN1
SCHEMBL31616803 0.86 KMT2A (0.61) NSD2MMP14FGBKMT2AMEN1
SCHEMBL20333922 0.80 NSD2 (0.82) NSD2MMP14FGBKMT2AMEN1
SCHEMBL8426997 0.80 TOP2B (0.64) NSD2MMP14FGBKMT2AMEN1
SCHEMBL27294872 0.79 TOP2B (0.62) NSD2MMP14FGBKMT2AMEN1
SCHEMBL7829735 0.78 NSD2 (0.55) NSD2MMP14FGBKMT2AMEN1
SCHEMBL20333884 0.76 FGB (0.53) NSD2MMP14FGBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 — — US disclosed
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 — — US disclosed
EP-3558235-B1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION OREAL (FR) 2021-09-08 — — EP disclosed
WO-2018115337-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2018-06-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION KRT18, CUTA, KLK5 NSD2 2000/4885MMP14 2125/4885FGB 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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