SCHEMBL8426997

SCHEMBL8426997

O=C1c2ccccc2C(=O)c2c(NCCOCCO)ccc(NCCOCCO)c21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2B Q02880 1/20 0.64
KMT2A Q03164 6/20 0.57
MEN1 O00255 5/20 0.57
BLM P54132 4/20 0.57
POLB P06746 3/20 0.57
NSD2 O96028 3/20 0.57
RXFP1 Q9HBX9 1/20 0.57
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
MTOR P42345 2/20 0.54
SIRT2 Q8IXJ6 1/20 0.54
LMNA P02545 5/20 0.49
SMN1; SMN2 Q16637 5/20 0.49
MAPT P10636 5/20 0.49
MAPK1 P28482 4/20 0.49
HTT P42858 4/20 0.49
RECQL P46063 3/20 0.49
NPSR1 Q6W5P4 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
ALDH1A1 P00352 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27294872 0.98 TOP2B (0.62) TOP2BKMT2AMEN1BLMPOLB
SCHEMBL20334359 0.93 TOP2B (0.57) TOP2BKMT2AMEN1BLMPOLB
SCHEMBL8429091 0.93 TOP2B (0.57) TOP2BKMT2AMEN1BLMPOLB
SCHEMBL16343733 0.91 TOP2B (0.61) TOP2BKMT2AMEN1BLMPOLB
SCHEMBL16344455 0.91 TOP2B (0.61) TOP2BKMT2AMEN1BLMPOLB
SCHEMBL13592574 0.90 TOP2B (0.59) TOP2BKMT2AMEN1BLMPOLB
SCHEMBL7112285 0.90 KMT2A (0.62) TOP2BKMT2AMEN1BLMPOLB
SCHEMBL10067502 0.89 TOP2B (0.61) TOP2BKMT2AMEN1BLMPOLB
Hydrochloric Acid SCHEMBL9502000 0.89 TOP2B (0.71) TOP2BKMT2AMEN1BLMPOLB
SCHEMBL14110308 0.89 TOP2B (0.58) TOP2BKMT2AMEN1BLMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9259380-B2 Means for dyeing and/or matting keratinic fibres containing novel 1,4 diaminoanthraquinone dyes HENKEL AG & CO. KGAA (DE) 2016-02-16 US claimed
US-20150007851-A1 MEANS FOR DYEING AND/OR MATTING KERATINIC FIBRES CONTAINING NOVEL 1,4 DIAMINOANTHRAQUINONE DYES HENKEL AG & CO. KGAA (DE) 2015-01-08 US claimed
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
EP-3558235-B1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION OREAL (FR) 2021-09-08 EP disclosed
WO-2018115337-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2018-06-28 WO disclosed
US-9259380-B2 Means for dyeing and/or matting keratinic fibres containing novel 1,4 diaminoanthraquinone dyes HENKEL AG & CO. KGAA (DE) 2016-02-16 US disclosed
US-9259380-B2 Means for dyeing and/or matting keratinic fibres containing novel 1,4 diaminoanthraquinone dyes HENKEL AG & CO. KGAA (DE) 2016-02-16 US disclosed
US-9259380-B2 Means for dyeing and/or matting keratinic fibres containing novel 1,4 diaminoanthraquinone dyes HENKEL AG & CO. KGAA (DE) 2016-02-16 US disclosed
US-20150007851-A1 MEANS FOR DYEING AND/OR MATTING KERATINIC FIBRES CONTAINING NOVEL 1,4 DIAMINOANTHRAQUINONE DYES HENKEL AG & CO. KGAA (DE) 2015-01-08 US disclosed
US-20150007851-A1 MEANS FOR DYEING AND/OR MATTING KERATINIC FIBRES CONTAINING NOVEL 1,4 DIAMINOANTHRAQUINONE DYES HENKEL AG & CO. KGAA (DE) 2015-01-08 US disclosed
US-20150007851-A1 MEANS FOR DYEING AND/OR MATTING KERATINIC FIBRES CONTAINING NOVEL 1,4 DIAMINOANTHRAQUINONE DYES HENKEL AG & CO. KGAA (DE) 2015-01-08 US disclosed
WO-2013135503-A1 MEANS FOR DYEING AND/OR MATTING KERATINIC FIBRES CONTAINING NOVEL 1,4 DIAMINO-ANTHRAQUINONE DYES HENKEL AG & CO. KGAA (DE) 2013-09-19 WO disclosed
US-5942292-A Spacer for liquid crystal display and liquid crystal display made by using the same KAO CORPORATION (JP) 1999-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150007851-A1 MEANS FOR DYEING AND/OR MATTING KERATINIC FIBRES CONTAINING NOVEL 1,4 DIAMINOANTHRAQUINONE DYES KRT18, SAT1, KIF5A TOP2B 954/4885KMT2A 567/4885MEN1 1473/4885
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION KRT18, CUTA, KLK5 TOP2B 989/4885KMT2A 2181/4885MEN1 2794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.