Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617062 | 0.81 | CTSK (0.41) | CA1CA2 | |
| SCHEMBL4745237 | 0.81 | CTSK (0.41) | CA1CA2 | |
| SCHEMBL3617063 | 0.81 | CTSK (0.41) | CA1CA2 | |
| SCHEMBL2225087 | 0.81 | ITGB3 (0.41) | ITGB3ITGA2BRAB9A | |
| SCHEMBL30759826 | 0.80 | LMNA (0.39) | SMN1; SMN2 | |
| SCHEMBL3822519 | 0.80 | SMN1; SMN2 (0.42) | ITGB3ITGA2BRAB9ABIRC2NPC1 | |
| SCHEMBL15528058 | 0.79 | RAB9A (0.42) | RAB9AACHENPC1SMN1; SMN2 | |
| SCHEMBL1863959 | 0.79 | BTN3A1 (0.33) | — | |
| SCHEMBL1696818 | 0.77 | CA1 (0.46) | RAB9ACA1CA2EPHX1ACHE | |
| SCHEMBL20683487 | 0.77 | CA1 (0.46) | RAB9ACA1CA2EPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351925-A1 | PRODRUGS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002055485-A1 | PRODRUGS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2002-07-18 | — | — | WO | disclosed |