SCHEMBL7112523

SCHEMBL7112523

CC(Cc1cc(N)cc(O)c1)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.39
TBXAS1 P24557 2/20 0.37
SLC7A5 Q01650 1/20 0.36
PLA2G10 O15496 3/20 0.36
PLA2G2A P14555 3/20 0.36
PLA2G1B P04054 1/20 0.36
PLA2G5 P39877 1/20 0.36
PLA2G2C Q5R387 1/20 0.36
PLA2G12B Q9BX93 1/20 0.36
PLA2G12A Q9BZM1 1/20 0.36
PLA2G2F Q9BZM2 1/20 0.36
PLA2G3 Q9NZ20 1/20 0.36
PLA2G2E Q9NZK7 1/20 0.36
PLA2G2D Q9UNK4 1/20 0.36
SIRT5 Q9NXA8 1/20 0.35
GABRR1 P24046 2/20 0.34
ADRB2 P07550 2/20 0.33
PTGER1 P34995 1/20 0.33
PTGER4 P35408 1/20 0.33
PTGER3 P43115 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1067198 0.76 PLA2G10 (0.50) FFAR1TBXAS1SLC7A5PLA2G10PLA2G2A
SCHEMBL18080782 0.75 TBXAS1 (0.49) FFAR1TBXAS1PLA2G10PLA2G2APLA2G1B
SCHEMBL15568884 0.74 TBXAS1 (0.51) FFAR1TBXAS1SLC7A5
SCHEMBL15134789 0.74 TBXAS1 (0.51) FFAR1TBXAS1SLC7A5
SCHEMBL12200630 0.74 TBXAS1 (0.51) FFAR1TBXAS1SLC7A5
SCHEMBL3658555 0.74 GRIA2 (0.54) FFAR1TBXAS1PLA2G10PLA2G2APLA2G1B
SCHEMBL6423007 0.74 ESR1 (0.43) ADRB2
SCHEMBL2498139 0.74 GRIA2 (0.54) FFAR1TBXAS1PLA2G10PLA2G2APLA2G1B
SCHEMBL12200634 0.74 LMNA (0.48) TBXAS1SIRT5
SCHEMBL3654636 0.74 GRIA2 (0.54) FFAR1TBXAS1PLA2G10PLA2G2APLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030109682-A1 Maytansines and maytansine conjugates SANTI DANIEL (US) 2003-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109682-A1 Maytansines and maytansine conjugates AREG, HDGF, GHITM FFAR1 2724/4885TBXAS1 1388/4885SLC7A5 488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.