Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23824708 | 0.81 | AOC3 (0.49) | CYP1A2CYP2C9HSD17B10PDE5APDE9A | |
| SCHEMBL18782928 | 0.78 | CYP1A2 (0.43) | CYP1A2CYP2C9HSD17B10PDE5APDE9A | |
| SCHEMBL889024 | 0.77 | HRH4 (0.55) | CYP1A2CYP2C9HSD17B10P4HTMGPR17 | |
| SCHEMBL3396659 | 0.77 | CYP1A2 (0.42) | CYP1A2CYP2C9HSD17B10PDE5APDE9A | |
| SCHEMBL5201259 | 0.74 | PDE9A (0.40) | CYP1A2CYP2C9HSD17B10PDE9AP4HTM | |
| SCHEMBL7537525 | 0.70 | AOC3 (0.46) | HSD17B10MAPTTBXAS1 | |
| SCHEMBL9314265 | 0.69 | KEAP1 (0.50) | CYP1A2CYP2C9HSD17B10GPR17KDM4E | |
| SCHEMBL26970720 | 0.68 | TSHR (0.45) | HSD17B10PDE5APDE9AP4HTMNPSR1 | |
| SCHEMBL31561464 | 0.67 | FFAR1 (0.54) | PDE5APDE9AGPR17KDM4EGLA | |
| SCHEMBL15773979 | 0.67 | NPSR1 (0.44) | PDE5APDE9AP4HTMNPSR1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1350507-A1 | Delivery of a substance to a pre-determinated site | Applied NanoSystems B.V. (NL) | 2003-10-08 | — | — | EP | disclosed |
| WO-1998048020-A2 | MAMMALIAN UBIQUITIN-ISOPEPTIDASES THAT CONTROL CELL PROLIFERATION | ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 1998-10-29 | — | — | WO | disclosed |