SCHEMBL3396659

SCHEMBL3396659

O=C(O)CCc1cnc(S)[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ P4HTM Q9NXG6 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.38
▸ PRKAG1 P54619 1/20 0.38
▸ PRKAA2 P54646 1/20 0.38
▸ PRKAA1 Q13131 1/20 0.38
▸ PRKAB1 Q9Y478 1/20 0.38
▸ NR1H4 Q96RI1 1/20 0.38
▸ TBXAS1 P24557 1/20 0.37
▸ CHRM1 P11229 1/20 0.37
▸ APEX1 P27695 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ KEAP1 Q14145 1/20 0.36
▸ PLAU P00749 1/20 0.36
▸ PDE5A O76074 1/20 0.35
▸ PDE9A O76083 1/20 0.35
▸ HDAC6 Q9UBN7 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16886923 0.79 KDM4E (0.40) CYP1A2CYP2C9HSD17B10KDM4EALDH1A1
SCHEMBL18782928 0.78 CYP1A2 (0.43) CYP1A2CYP2C9HSD17B10P4HTMNPSR1
SCHEMBL23824708 0.77 AOC3 (0.49) CYP1A2CYP2C9HSD17B10P4HTMNPSR1
SCHEMBL889024 0.77 HRH4 (0.55) CYP1A2CYP2C9HSD17B10P4HTMNPSR1
SCHEMBL7112651 0.77 CYP1A2 (0.42) CYP1A2CYP2C9HSD17B10P4HTMNPSR1
SCHEMBL5201259 0.74 PDE9A (0.40) CYP1A2CYP2C9HSD17B10P4HTMNPSR1
SCHEMBL1065163 0.72 SLC7A5 (0.53) CYP1A2CYP2C9HSD17B10NPSR1NR1H4
SCHEMBL9314265 0.69 KEAP1 (0.50) CYP1A2CYP2C9HSD17B10TBXAS1CHRM1
SCHEMBL10563288 0.69 TAAR1 (0.50) —
SCHEMBL13201954 0.68 SLC22A4 (0.38) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5126229-A No background contamination FUJI PHOTO FILM CO., LTD. (JP) 1992-06-30 — — US claimed
EP-3086177-A1 METHOD FOR PREPARING A LITHOGRAPHIC PRINTING PLACE PRECURSOR Fujifilm Corporation (JP) 2016-10-26 — — EP disclosed
EP-3086176-A1 A LITHOGRAPHIC PRINTING METHOD Fujifilm Corporation (JP) 2016-10-26 — — EP disclosed
US-20110054212-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS OOHASHI HIDEKAZU 2011-03-03 — — US disclosed
EP-1754597-B1 Lithographic printing plate precursor and lithographic printing process FUJIFILM CORP (JP) 2010-12-29 — — EP disclosed
US-7858291-B2 imagewise exposure, protective layer comprises water-soluble polyvinyl alcohol; phosphonium salts FUJIFILM CORPORATION (JP) 2010-12-28 — — US disclosed
US-7851126-B2 Including an aromatic diphosphonium compound along with an addition polymerization promoter, unsaturated compound, protective layeron an sluminium support; laser recording having excellent ink receptibility during printing and printing durability; strength; on-press development; image strength FUJIFILM CORPORATION (JP) 2010-12-14 — — US disclosed
US-20070042293-A1 Including an aromatic diphosphonium compound along with an addition polymerization promoter, unsaturated compound, protective layeron an sluminium support; laser recording having excellent ink receptibility during printing and printing durability; strength; on-press development; image strength FUJI PHOTO FILM CO., LTD. 2007-02-22 — — US disclosed
EP-1754597-A2 Lithographic printing plate precursor and lithographic printing process Fuji Photo Film Co., Ltd. (JP) 2007-02-21 — — EP disclosed
US-20060194150-A1 imagewise exposure, protective layer comprises water-soluble polyvinyl alcohol; phosphonium salts FUJI PHOTO FILM CO., LTD. 2006-08-31 — — US disclosed
US-6174646-B1 IMAGEWISE HEATING OR EXPOSING IMAGE FORMING MATERIAL TO LASER WHEREIN IMAGE FORMING MATERIAL COMPRISES SUPPORT HAVING RADIATION SENSITIVE LAYER CONTAINING DYE, AN ACID GENERATING COMPOUND CAPABLE OF GENERATING ACID ON IRRADIATION KONICA CORPORATION (JP) 2001-01-16 — — US disclosed
US-5994031-A DEVELOPMENT; WASHING KONICA CORPORATION (JP) 1999-11-30 — — US disclosed
EP-0911153-A1 Image forming method KONICA CORPORATION (JP) 1999-04-28 — — EP disclosed
EP-0516372-B1 Concentrated dampening water composition for lithographic printing FUJI PHOTO FILM CO LTD (JP) 1996-04-24 — — EP disclosed
US-5221330-A Hydrophilic film-forming polymer, buffer, water miscible organic solvent, micelle-forming compound, water FUJI PHOTO FILM CO., LTD. (JP) 1993-06-22 — — US disclosed
EP-0516372-A1 Concentrated dampening water composition for lithographic printing FUJI PHOTO FILM CO., LTD. (JP) 1992-12-02 — — EP disclosed
US-5149614-A DEVELOPER COMPOSITIONS FOR PS PLATES AND METHOD FOR DEVELOPING THE SAME WHEREIN THE DEVELOPER COMPOSITION CONTAINS A SURFACTANT HAVING AN ARYL GROUP, AN OXYALKYLENE GROUP AND A SULFATE ESTER OR SULFONIC ACID GROUP FUJI PHOTO FILM CO., LTD. (JP) 1992-09-22 — — US disclosed
US-5126229-A No background contamination FUJI PHOTO FILM CO., LTD. (JP) 1992-06-30 — — US disclosed
US-5047309-A Photosensitive diazonium recording material with sulfur compound containing undercoat layer FUJI PHOTO FILM CO., LTD. (JP) 1991-09-10 — — US disclosed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054212-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS FLNA, PFN1, FLNB CYP1A2 3266/4885CYP2C9 3746/4885HSD17B10 3856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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