Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772552 | 1.00 | ESR1 (0.33) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL7729519 | 0.93 | ABCC2 (0.34) | ABCC2 | |
| SCHEMBL6623137 | 0.89 | ESR1 (0.32) | ESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL7633400 | 0.86 | CACNA1C (0.34) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL7730467 | 0.85 | FAP (0.45) | — | |
| SCHEMBL6887614 | 0.85 | PTGS1 (0.33) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL7629819 | 0.85 | CACNA1C (0.35) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL7633322 | 0.85 | PTGS1 (0.33) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL7638706 | 0.84 | PTGS1 (0.33) | ESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL5236238 | 0.84 | PTGS1 (0.33) | ESR1PTGS1PDE4ACACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030022881-A1 | Novel carbapenem derivatives of quarternary salt type | MEIJI SEIKA KAISHA, LTD. (JP) | 2003-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022881-A1 | Novel carbapenem derivatives of quarternary salt type | DHPS, HDHD5, RRP15 | ESR1 4807/4885PTGS1 2945/4885PDE4A 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.