Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 16/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4169629 | 0.86 | PGR (0.41) | PGRARNR3C1 | |
| SCHEMBL29918234 | 0.86 | PGR (0.53) | PGRARNR3C1NR3C2 | |
| SCHEMBL5032324 | 0.86 | PGR (0.53) | PGRARNR3C1NR3C2 | |
| SCHEMBL6928534 | 0.79 | PGR (0.55) | PGRARNR3C1NR3C2 | |
| Hydrochloric Acid SCHEMBL6723833 | 0.78 | PGR (0.54) | PGRARNR3C1NR3C2 | |
| SCHEMBL2393047 | 0.78 | PGR (0.73) | PGRARNR3C1NR3C2 | |
| SCHEMBL6294955 | 0.76 | PGR (0.52) | PGRARNR3C1NR3C2 | |
| SCHEMBL13875735 | 0.74 | PGR (0.46) | PGRARNR3C1NR3C2 | |
| SCHEMBL2394299 | 0.74 | PGR (0.55) | PGRARNR3C1NR3C2 | |
| SCHEMBL4160644 | 0.73 | AR (0.53) | PGRARNR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021118728-A2 | GLUCOCORTICOID RECEPTOR RADIOLIGANDS AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-17 | — | — | WO | disclosed |
| US-6608216-B2 | Preparing biaryl atropisomers; chirality transfer from stereogenic center of secondary alcohol to biaryl stereogenic axis via regioselective intramolecular migration | ABBOTT LABORATORIES | 2003-08-19 | — | — | US | disclosed |
| US-20030073844-A1 | Process for the preparation of chiral glucocorticoid receptor agents | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073844-A1 | Process for the preparation of chiral glucocorticoid receptor agents | NR3C1, NR3C2, MC2R | PGR 286/4885AR 35/4885NR3C1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.