Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.45 |
| ▸ | CALCR | P30988 | 6/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805702 | 0.88 | RAMP3 (0.55) | PIN1RAMP3CALCRF2 | |
| SCHEMBL6176082 | 0.81 | RAMP3 (0.54) | RAMP3CALCR | |
| SCHEMBL6176075 | 0.80 | RAMP3 (0.52) | RAMP3CALCR | |
| SCHEMBL6831579 | 0.78 | CAPN1 (0.51) | FOLH1CAPN1PIN1TDP1RAMP3 | |
| SCHEMBL7577396 | 0.77 | TDP1 (0.64) | FOLH1CASP3CASP1CASP2CASP7 | |
| SCHEMBL5406043 | 0.76 | TDP1 (0.56) | FOLH1CASP3CASP1CASP2CASP7 | |
| SCHEMBL30128547 | 0.76 | PLG (0.47) | FOLH1PIN1TDP1F2PLG | |
| SCHEMBL9925691 | 0.76 | PLG (0.62) | FOLH1CASP3CASP1CASP2CASP7 | |
| SCHEMBL6534725 | 0.75 | CASP3 (0.55) | FOLH1CASP3CASP1CASP2CASP7 | |
| SCHEMBL16500105 | 0.74 | F2 (0.48) | FOLH1CAPN1PIN1TDP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309622-A2 | LAT PEPTIDES AND THEIR USE IN ASSAYS FOR IDENTIFYING IMMUNOSUPPRESSANTS | Novartis AG (CH) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012275-A2 | LAT PEPTIDES AND THEIR USE IN ASSAYS FOR IDENTIFYING IMMUNOSUPPRESSANTS | NOVARTIS AG (CH) | 2002-02-14 | — | — | WO | disclosed |