Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.62 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.62 |
| ▸ | F2 | P00734 | 2/20 | 0.62 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | MAFG | O15525 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15397822 | 0.80 | PLG (0.64) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15397969 | 0.80 | PLG (0.64) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL14521652 | 0.79 | ELANE (0.44) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15397928 | 0.77 | PLG (0.56) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL7113668 | 0.76 | FOLH1 (0.50) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL18103817 | 0.75 | CASP3 (0.48) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL18116208 | 0.75 | CASP3 (0.48) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15397835 | 0.74 | PRSS1 (0.56) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15397856 | 0.74 | PRSS1 (0.56) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15397891 | 0.73 | PLG (0.55) | PLGPRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140056964-A1 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2014-02-27 | — | — | US | disclosed |
| WO-2012076985-A2 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140056964-A1 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | GZMB, PRF1, SERPINB1 | PLG 134/4885PRSS1 267/4885PRSS2 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.