Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | COASY | Q13057 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016006 | 0.89 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1COASY | |
| SCHEMBL7122586 | 0.89 | CSNK2A2 (0.40) | CSNK2A2CSNK2BCSNK2A1COASYKDM4E | |
| SCHEMBL7120039 | 0.84 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1COASYKDM4E | |
| SCHEMBL7209326 | 0.83 | RHEB (0.44) | CSNK2A2CSNK2BCSNK2A1COASYKDM4E | |
| SCHEMBL7208992 | 0.79 | HTT (0.56) | CSNK2A2CSNK2BCSNK2A1COASYKDM4E | |
| SCHEMBL7903051 | 0.79 | CSNK2A2 (0.49) | CSNK2A2CSNK2BCSNK2A1COASYKDM4E | |
| SCHEMBL7734462 | 0.77 | AR (0.40) | CSNK2A2CSNK2BCSNK2A1KDM4EALDH1A1 | |
| SCHEMBL29720357 | 0.76 | GAA (0.49) | KDM4EALDH1A1HTTARMCHR1 | |
| SCHEMBL439758 | 0.76 | GAA (0.49) | KDM4EALDH1A1HTTARMCHR1 | |
| SCHEMBL7121298 | 0.75 | CBFB (0.36) | CSNK2A2CSNK2BCSNK2A1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970100-B1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-11-12 | — | — | EP | disclosed |
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |
| EP-0970100-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035977-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |