Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120039 | 0.89 | CSNK2A2 (0.42) | CBFBCSNK2A2CSNK2BCSNK2A1HRH4 | |
| SCHEMBL8016006 | 0.85 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL7114594 | 0.75 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL7122586 | 0.71 | CSNK2A2 (0.40) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL7214338 | 0.69 | KDM4E (0.43) | CBFBCSNK2A2CSNK2BCSNK2A1HRH4 | |
| SCHEMBL899953 | 0.67 | ALDH1A1 (0.36) | ALDH1A1LMNA | |
| SCHEMBL7208992 | 0.64 | HTT (0.56) | CBFBCSNK2A2CSNK2BCSNK2A1HRH4 | |
| SCHEMBL7209326 | 0.64 | RHEB (0.44) | CSNK2A2CSNK2BCSNK2A1EGLN1ALDH1A1 | |
| SCHEMBL7734462 | 0.62 | AR (0.40) | CSNK2A2CSNK2BCSNK2A1EGLN1ALDH1A1 | |
| SCHEMBL3469733 | 0.61 | CBFB (0.44) | CBFBHRH4EGLN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970100-B1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-11-12 | — | — | EP | disclosed |