Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CBFB | Q13951 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | COASY | Q13057 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121298 | 0.89 | CBFB (0.36) | CSNK2A2CSNK2BCSNK2A1CBFBHRH4 | |
| SCHEMBL7114594 | 0.84 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL7122586 | 0.80 | CSNK2A2 (0.40) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL7214338 | 0.78 | KDM4E (0.43) | CSNK2A2CSNK2BCSNK2A1CBFBHRH4 | |
| SCHEMBL8016006 | 0.75 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1COASY | |
| SCHEMBL7209326 | 0.72 | RHEB (0.44) | CSNK2A2CSNK2BCSNK2A1EGLN1ALDH1A1 | |
| SCHEMBL7208992 | 0.72 | HTT (0.56) | CSNK2A2CSNK2BCSNK2A1CBFBHRH4 | |
| SCHEMBL7734462 | 0.70 | AR (0.40) | CSNK2A2CSNK2BCSNK2A1EGLN1ALDH1A1 | |
| SCHEMBL3469733 | 0.69 | CBFB (0.44) | CBFBHRH4EGLN1ALDH1A1LMNA | |
| SCHEMBL7903051 | 0.69 | CSNK2A2 (0.49) | CSNK2A2CSNK2BCSNK2A1EGLN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970100-B1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-11-12 | — | — | EP | disclosed |
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |