Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | COASY | Q13057 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122586 | 0.88 | CSNK2A2 (0.40) | RHEBCSNK2A2CSNK2BCSNK2A1COASY | |
| SCHEMBL7903051 | 0.86 | CSNK2A2 (0.49) | RHEBCSNK2A2CSNK2BCSNK2A1COASY | |
| SCHEMBL7114594 | 0.83 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1COASYKDM4E | |
| SCHEMBL7208992 | 0.81 | HTT (0.56) | CSNK2A2CSNK2BCSNK2A1COASYEGLN1 | |
| SCHEMBL439758 | 0.77 | GAA (0.49) | RHEBEGLN1KDM4EALDH1A1HTT | |
| SCHEMBL29720357 | 0.77 | GAA (0.49) | RHEBEGLN1KDM4EALDH1A1HTT | |
| SCHEMBL7208967 | 0.74 | ADORA1 (0.52) | CSNK2A2CSNK2BCSNK2A1COASYEGLN1 | |
| SCHEMBL8016006 | 0.74 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1COASY | |
| SCHEMBL7214221 | 0.73 | RIPK1 (0.46) | RHEBEGLN1 | |
| SCHEMBL8367465 | 0.73 | KDM4E (0.48) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617315-B1 | Sugar-substituted benzimidazole derivatives are used for the treatment or prophylaxis of restenosis, particularly following angioplasty | CHAMBERLAIN STANLEY DAWES (US) | 2003-09-09 | — | — | US | disclosed |
| US-6204249-B1 | L-benzimidazole nucleosides | GLAXO WELLCOME INC. | 2001-03-20 | — | — | US | disclosed |