SCHEMBL711461

SCHEMBL711461

C(=Cc1cnc2ccccc2n1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.59
RAB9A P51151 6/20 0.59
NPC1 O15118 5/20 0.59
PKM P14618 2/20 0.59
LMNA P02545 2/20 0.59
PDGFRB P09619 2/20 0.58
PDGFRA P16234 2/20 0.58
PAX8 Q06710 1/20 0.57
MAPT P10636 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
POLB P06746 1/20 0.53
GRM4 Q14833 5/20 0.51
ALDH1A1 P00352 6/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
HPGD P15428 3/20 0.50
HDAC6 Q9UBN7 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
GRM5 P41594 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL711460 1.00 KDM4E (0.59) KDM4ERAB9ANPC1PKMLMNA
SCHEMBL12923109 0.94 PAX8 (0.63) KDM4ERAB9ANPC1PKMLMNA
SCHEMBL708674 0.90 PAX8 (0.56) KDM4ERAB9ANPC1PKMLMNA
SCHEMBL708673 0.90 PAX8 (0.56) KDM4ERAB9ANPC1PKMLMNA
SCHEMBL707786 0.89 PDGFRB (0.50) KDM4ERAB9ANPC1PKMLMNA
SCHEMBL707785 0.89 PDGFRB (0.50) KDM4ERAB9ANPC1PKMLMNA
SCHEMBL708683 0.86 PAX8 (0.56) KDM4ERAB9ANPC1PKMLMNA
SCHEMBL714075 0.86 PAX8 (0.56) KDM4ERAB9ANPC1PKMLMNA
SCHEMBL710216 0.86 PAX8 (0.56) KDM4ERAB9ANPC1PKMLMNA
SCHEMBL708372 0.86 PAX8 (0.56) KDM4ERAB9ANPC1PKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4602081-A1 PHOTO-SWITCHABLE CHEMISTRY FOR REVERSIBLE HYDROGELS AND REUSABLE FLOW CELLS Illumina, Inc. (US) 2025-08-20 EP claimed
WO-2024081563-A1 PHOTO-SWITCHABLE CHEMISTRY FOR REVERSIBLE HYDROGELS AND REUSABLE FLOW CELLS ILLUMINA, INC. (US) 2024-04-18 WO claimed
EP-4602081-A1 PHOTO-SWITCHABLE CHEMISTRY FOR REVERSIBLE HYDROGELS AND REUSABLE FLOW CELLS Illumina, Inc. (US) 2025-08-20 EP disclosed
US-20240150508-A1 PHOTO-SWITCHABLE CHEMISTRY FOR REVERSIBLE HYDROGELS AND REUSABLE FLOW CELLS ILLUMINA, INC. (US) 2024-05-09 US disclosed
CN-117924166-A Direct alkenylation of methylazaheteroaryl compounds and benzyl alcohols 常州大学 2024-04-26 CN disclosed
WO-2024081563-A1 PHOTO-SWITCHABLE CHEMISTRY FOR REVERSIBLE HYDROGELS AND REUSABLE FLOW CELLS ILLUMINA, INC. (US) 2024-04-18 WO disclosed
CN-107118586-A The purposes of the vinyl compound of nitrogen heterocycle substitution 中国科学技术大学 2017-09-01 CN disclosed
CN-104529889-A Dehydration C-alkylation method for heterocyclic methyl compound UNIV WENZHOU 2015-04-22 CN disclosed
US-8124625-B2 enhancing the expression of apoAI; prevention or therapy of dislipidemia SHIONOGI & CO., LTD. (JP) 2012-02-28 US disclosed
US-8053445-B2 Utilities of olefin derivatives SHIONOGI & CO., LTD. (JP) 2011-11-08 US disclosed
US-20090036457-A1 Utilities of olefin derivatives YAMAMORI TERUO 2009-02-05 US disclosed
US-20040242615-A1 Utilities of olefin derivatives SHIONOGI & CO., LTD. (JP) 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242615-A1 Utilities of olefin derivatives APOL1, NR1H2, APOB KDM4E 4415/4885RAB9A 4723/4885NPC1 19/4885
US-20090036457-A1 Utilities of olefin derivatives APOL1, APOB, NR1H2 KDM4E 4647/4885RAB9A 4606/4885NPC1 48/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.