SCHEMBL708372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL708373	1.00	PAX8 (0.56)	PAX8CYP19A1MAOAMAOBRAB9A
	SCHEMBL12923109	0.91	PAX8 (0.63)	PAX8RAB9ANPC1MEN1MAPT
	SCHEMBL711461	0.86	KDM4E (0.59)	PAX8RAB9ANPC1MEN1MAPT
	SCHEMBL711460	0.86	KDM4E (0.59)	PAX8RAB9ANPC1MEN1MAPT
	SCHEMBL708683	0.83	PAX8 (0.56)	PAX8RAB9ANPC1MEN1MAPT
	SCHEMBL712709	0.83	RAB9A (0.64)	PAX8RAB9ANPC1MEN1MAPT
	SCHEMBL710216	0.83	PAX8 (0.56)	PAX8RAB9ANPC1MEN1MAPT
	SCHEMBL714074	0.83	PAX8 (0.56)	PAX8RAB9ANPC1MEN1MAPT
	SCHEMBL714075	0.83	PAX8 (0.56)	PAX8RAB9ANPC1MEN1MAPT
	SCHEMBL708682	0.83	PAX8 (0.56)	PAX8RAB9ANPC1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.