Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510696 | 0.89 | TSHR (0.60) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL231457 | 0.88 | KMT2A (0.72) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL11054244 | 0.86 | KMT2A (0.70) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| Potassium Ion SCHEMBL11056843 | 0.86 | KMT2A (0.70) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL8447120 | 0.86 | KMT2A (0.70) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| Hydrochloric Acid SCHEMBL6222540 | 0.86 | KMT2A (0.70) | KMT2AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL206197 | 0.86 | TSHR (0.57) | KMT2AALDH1A1CYP3A4ALOX15RAB9A | |
| SCHEMBL7115345 | 0.85 | KMT2A (0.54) | KMT2AALDH1A1TDP1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10824597 | 0.85 | TSHR (0.55) | KMT2AALDH1A1CYP3A4ALOX15RAB9A | |
| SCHEMBL27635677 | 0.84 | TP53 (0.69) | KMT2AALDH1A1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130343-A1 | Fat accumulation-modulating compounds | ADIPOGENIX, INC. (US) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130343-A1 | Fat accumulation-modulating compounds | FABP4, LIPC, PLIN1 | KMT2A 1569/4885ALDH1A1 1223/4885CYP3A4 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.